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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight management in addition to a reduced-calorie diet and physical exercise.

Using two separate drugs to lose weight naturally can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you ought to err on the side of caution and permit the FDA do its job and demand some study be done so that the public recognizes the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies have been in business to generate income and that they would say anything to keep people on his or her medications.

Researchers discovered that participants using this drug for the year, lost weight within one month and have kept the weight off during the entire 56 weeks in the study. Contrave can be a combination in the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which can be made up of several active ingredient, that might make them more potent and safer.

Combo-pilling will be the newest fad or also the newest in the future under scrutiny and so it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular is the fact that at the time of right now there are not any long term prescription slimming capsules that have been licensed by the FDA aside from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be authorized by the FDA.

Seizures really are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug also can raise hypertension and pulse rate, and really should not be used in individuals with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure level and heartrate and must not be used in patients with uncontrolled high hypertension, as well as by a person with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients using a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients on the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking.

New UCLA study on smokers with mental, drug, and alcohol problems


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