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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment choice for chronic weight-loss in addition to a reduced-calorie diet and physical activity.

Using two separate drugs to lose weight can be very effective you'll find combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the those who go through it you ought to err along the side of caution and let the FDA do its job and demand some study be done in order that the public recognizes the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to earn money and that they would say anything to keep people on their own medications.

Researchers found that participants using this drug for the year, dropped a few pounds within four weeks and have kept the weight off throughout the 56 weeks of the study. Contrave is often a combination of the drugs naltrexone and bupropion, which seems to reflect a fresh trend of weight-loss drugs which can be made up of multiple active ingredient, which might make them far better and safer.

Combo-pilling will be the newest fad or also the newest ahead under scrutiny and thus it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular could be the fact that since right now there aren't any long term prescription weight loss supplements that have been licensed by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be approved by the FDA.

Seizures certainly are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug may also raise blood pressure and heartrate, and really should not be used in people with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure and heart rate and must not used in patients with uncontrolled high blood pressure levels, in addition to by you are not heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients having a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients towards the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.

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