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It was found out that naltrexone and bupropion combined, which can be marketed down the road as Contrave, provide better weight loss results than exercise and dieting alone.

Using two separate drugs to shed pounds can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with weight loss and the those who go through it you should err on the side of caution and allow FDA do its job and demand some investigation be done so that the public recognizes the side effects and dangers of the medications before we drive them. Keep in mind that drug companies have been in business to earn money and that they would say almost anything to keep people on his or her medications.

Researchers found that participants taking this drug for a year, lost weight within one month and have kept the load off through the entire 56 weeks with the study. Contrave can be a combination of the drugs naltrexone and bupropion, which usually reflect a brand new trend of weight-loss drugs which might be made up of many active ingredient, which may make them far better and safer.

Combo-pilling will be the newest fad or in addition to this the newest to come under scrutiny and so it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular will be the fact that by right now there aren't long term prescription weightloss pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be approved by the FDA.

Seizures can be a side effect with Contrave and must not be taken in people with seizure disorders. The drug also can raise blood pressure level and heartrate, and really should not be used in individuals with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure level and heart rate and must stop used in patients with uncontrolled high blood pressure level, and also by you are not heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients with a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients for the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation.

Approving a drug using this many potentially lethal unwanted side effects is inconsistent while using mission statement of the FDA. The power with the drug manufacturing lobby is blatantly evident inside approval of numerous drugs requiring 'post-marketing' studies which can be clearly significant to overall drug safety in the US.


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