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Contrave is looking very promising for anyone seeking an eating plan pill that work well. The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the benefit of the drug outweighs potential risk of a possible increase in blood pressure.

Using two separate drugs to shed pounds can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the those who go through it you should err along the side of caution and let the FDA do its job and demand some research be done so that the public understands the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies will be in business to generate money and that they would say anything to keep people on the medications.

Researchers found that participants investing in this drug for a year, dropped a few pounds within a month and have kept the weight off during the entire 56 weeks with the study. Contrave can be a combination of the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which are made up of more than one active ingredient, which might make them more efficient and safer.

Combo-pilling will be the newest fad or even better the newest into the future under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for weight loss has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular will be the fact that since right now there are no long term prescription diet pills that have been licensed by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be approved by the FDA.

Seizures certainly are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug also can raise blood pressure level and pulse rate, and really should not be used in people who have a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise hypertension and heart rate and must stop used in patients with uncontrolled high blood pressure, as well as by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients having a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients on the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking.

Approving a drug using this many potentially lethal unwanted side effects is inconsistent using the mission statement in the FDA. The power with the drug manufacturing lobby is blatantly evident within the approval of numerous drugs requiring 'post-marketing' studies which can be clearly significant to overall drug safety inside US.


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